Instructor

A general introduction to the chemistry and structure of nucleic acids. Brief notes on the structure of nucleic acids on the nanoscale, DNA curvature and flexibility and the experimental techniques that are used to study them.

The slides of the lectures: lecture given by Bruno Samorì

Pointers to additional materials:

Calladine, Drew, "Understanding DNA: the molecule and how it works."

Bloomfield, Crothers, Tinoco, "Nucleic Acids: Structures, Properties, and Functions"

Wikipedia: Nucleic acids, DNA, RNA, Atomic force microscope, Hydrogen bond, nucleobase, (no responsability for this material),

DNA structure images at Rutgers university

Nucleic acids nanotechnology

Making nanostructures by design exploiting the self-assembly of nucleic acids

The slides of the lectures: PDF (3MB)

Pointers to additional materials:

Ned Seeman's Scientific American Paper, and a recent review

An animation that explains the motion of the DNA biped walker (you should left-click on the PDF picture to start the animation)

Giampaolo Zuccheri